Faculty: Ted Inaba, PhD

Ted Inaba, PhDTed Inaba, PhD
Professor Emeritus
Department of Pharmacology and Toxicology

General Research Areas: Drug Metabolism, Pharmacogenetics, Drug Interactions
Genetic Variation of Drug Metabolizing Enzymes

NOT TAKING NEW GRADUATE STUDENTS

Selected Publications:

Trottier J, Verreault M, Grepper S, Monté D, Bélanger J, Kaeding J, Caron P, Inaba T, Barbier O. Human UDP-glucuronosyltransferase (UGT)1A3 enzyme conjugates chenodeoxycholic acid in the liver. Hepatology. 2006; 44:1158-1170.

Zhou Q, Matsumoto S, Ding LR, Fischer NE, Inaba T. The comparative Interaction of human and bovine serum albumins with CYP2C9 in human liver microsomes. Life Sci.2004; 75:2145-2155.

Xu BQ, Ishii M, Ding LR, Fischer NE, Inaba T. Interaction of serum proteins with CYP isoforms in human liver microsomes: Inhibitory effects of human and bovine albumin, alpha-globulins, alpha-1-acid glycoproteins and gamma-globulins on CYP2C19 and CYP2D6. Life Sci. 2003; 72:1953-1962.

Fukuen S, Fukuda T, Matsuda H, Sumida A, Yamamoto I, Inaba T, Azuma J. Identification of the novel splicing variants for the hPXR in human livers. Biochem Biophys Res Commun. 2002; 298:433-438. 

Fukuen S, Fukuda T, Maune H, Ikenaga Y, Yamamoto I, Inaba T, Azuma J: Novel detection assay by PCR-RFLP and frequency of CYP3A5 SNPs, CYP3A5*3 and *6, in a Japanese population. Pharmacogenetics. 2002; 12:331-334.

Jorge-Nebert LF, Eichelbaum M, Griese E-U, Inaba T, Arias TD: Analysis of six SNPs of NAT2 in Ngawbe and Embera Amerindians of Panama and determination of the Embera acetylation phenotype employing caffeine. Pharmacogenetics. 2002; 12:39-45.

Fayz S, Inaba T: Zidovudine azido-reductase in human liver microsomes: Activation by ethacrynic acid, dipyridamole and indomethacin and inhibition by human immunodeficiency virus protease inhibitors. Antimicrob Agents Chemother. 1998; 42:1654-1658.

Wilson AA, Inaba T, Fischer NE, Dixon LM, Nobrega J, DaSilva JN, Houle S: Derivatives of WAY 1000635 as potential imaging agents for 5-HT1A receptors: Synthesis, radiosynthesis, in vitro and in vivo evaluation. Nuclear Med Biol. 1998; 25:769-776. 

Contact:

Department of Pharmacolgy & Toxicology
Email:  t.inaba@utoronto.ca

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