Joanne Kotsopoulos, PhD

Joanne Kotsopoulos, PhDJoanne Kotsopoulos, PhD Joanne Kotsopoulos, PhD
Associate Professor
Scientist

CONTACT INFO

T. (416) 351-3732
joanne.kotsopoulos@wchospital.ca
www.womensresearch.ca

RESEARCH INTERESTS:

Cancer epidemiology (breast, ovarian), BRCA1/2 mutation carriers; Hereditary cancer

CLINICAL INTERESTS:

Prognostic factors, Prevention, Genetics, Biomarkers, Lifestyle

ACCEPTING: 

Currently teach and supervise both undergraduate and graduate students

APPOINTMENTS:

Chair in Population Studies, Cancer Care Ontario
Scientist, Women's College Research Institute
Associate Professor, Dalla Lana School of Public Health and Department of Nutritional Sciences, University of Toronto
Associate Professor, Dept. of Pharmacology & Toxicology

 

Dr. Joanne Kotsopoulos is a Scientist with the Familial Breast Cancer Research Unit at the Women’s College Research Institute, Women’s College Hospital and an Associate Professor at the Dalla Lana School of Public Health with a cross appointment at the Department of Nutritional Sciences at the University of Toronto (UofT). She received her PhD from the Department of Nutritional Sciences at UofT in 2007 and subsequently conducted her post-doctoral research training at the Brigham and Women’s Hospital/Harvard Medical School. While there, she took part in several studies investigating risk factors for both breast and ovarian cancer using the Nurses’ Health Study Cohorts and had the opportunity to work closely with several experts in nutritional sciences and cancer epidemiology.

Dr. Kotsopoulos directs molecular studies aimed at characterizing BRCA genes as haploinsufficient tumor suppressor genes and investigate whether one can modulate cancer risk by affecting gene or protein expression. The overall goal of her research is to provide women with a wider choice of less-invasive options to reduce their risk of breast and ovarian cancer.

She also leads several projects aimed to improve our understanding of factors that impact ovarian cancer prognosis, a highly fatal disease.

RESEARCH SYNOPSIS:

Dr. Kotsopoulos returned to Canada as an independent researcher in 2009 as a recipient of a Cancer Care Ontario Chair in Population Studies. She has been awarded the Canadian Gene Cure Foundation/CIHR Champion of Genetics Grant and the Canadian Cancer Society Career Development Award in Prevention. Her research program is dedicated at furthering our understanding of BRCA-associated breast and ovarian cancer with the intent of identifying strategies that confer substantial risk reduction and improve outcome. Her efforts include identifying inherent markers (host factors) in BRCA-mutation carriers. This research may translate into putative targets for chemoprevention.

Dr. Kotsopoulos directs molecular studies aimed at characterizing BRCA genes as haploinsufficient tumor suppressor genes and investigate whether one can modulate cancer risk by affecting gene or protein expression. The overall goal of her research is to provide women with a wider choice of less-invasive options to reduce their risk of breast and ovarian cancer.

She also leads several projects aimed to improve our understanding of factors that impact ovarian cancer prognosis, a highly fatal disease.

PUBLICATIONS:

View List of Publication here: https://www.ncbi.nlm.nih.gov/pubmed?cmd=Search&term=kotsopoulos%20j%5Bau%5D

TEACHING:

Dr. Kotsopoulos is actively involved in teaching and mentoring of both undergraduate and graduate student at UofT.

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