Professor Emeritus
Jane Mitchell
Pharmacology and Toxicology
PhD
Location
Medical Sciences Building
Address
Department of Pharmacology and Toxicology , 1 King's College Circle, Rm 4342, Toronto, Ontario Canada M5S 1A8
Research Interests
receptor pharmacology, signal transduction
Appointment Status
Primary
Accepting
Not accepting graduate students
Research in my laboratory focuses on several topics. CIHR-funded projects In the skeletal system investigate the effects of glucocorticoids on bone and muscle. We utilize mouse models to determine the molecular mechanisms through which glucocorticoids inhibit bone growth and cause osteoporosis. We also examine the effect of glucocorticoids on the skeletal system in mouse models of Duchenne muscular dystrophy.
Our NSERC-funded research projects investigate visual signalling systems using purified proteins to investigate the structural interactions between rhodopsin, G protein subunits, arrestin, receptor kinase and phospholipase C.