Research in my laboratory focuses on several topics. CIHR-funded projects In the skeletal system investigate the effects of glucocorticoids on bone and muscle. We utilize mouse models to determine the molecular mechanisms through which glucocorticoids inhibit bone growth and cause osteoporosis. We also examine the effect of glucocorticoids on the skeletal system in mouse models of Duchenne muscular dystrophy.
Our NSERC-funded research projects investigate visual signalling systems using purified proteins to investigate the structural interactions between rhodopsin, G protein subunits, arrestin, receptor kinase and phospholipase C.