Matthieu Schapira

Pharmacology and Toxicology


Structural Genomics Consortium
101 College St. , South Tower, Rm 713, Toronto, Ontario Canada M5G 1L6
Research Interests
computational chemistry
Appointment Status
TBC - Contact faculty member for details

Matthieu holds a M.Sc degree in chemistry from the National Superior Chemistry School, Nancy, France, and a Ph.D in biochemistry from Ecole Normale Superieure, Paris. After graduating in 1995, he completed a couple post-docs in protein crystallography and computational chemistry at New York University Medical Center. In 2000, he joined Molsoft, a San-Diego based biotech, as senior research scientist. In 2003, he moved to Lyon, France, to lead structure-based drug design at Aptanomics/Imaxio, a drug discovery start-up. In 2007, he joined the SGC (Structural Genomics Consortium) as head of research informatics. Matthieu holds an Associate Professor cross-appointment with the Department of Pharmacology and Toxicology at University of Toronto, and an adjunct Associate Professor position with the Department of Pharmacology at New York University.

SGC Toronto’s Research Informatics group has three distinct roles. (1) Research: we apply computational chemistry tools to analyze protein structures and support the development of chemical inhibitors. We also analyze cancer genomics data. (2) Tools: we develop web interfaces, such as Chromohub, to easily navigate structural, chemical and genomic data. (3) Databases: we manage the wealth of biological and chemical data generated at SGC-Toronto.