Participate in Collaborative Research with Two of the World's Leading Universities
The Toronto-Melbourne Research Training Group is currently recruiting PhD candidates. All candidates are fully funded and will commence at the University of Toronto, to complete their coursework requirements. Candidates will all spend a minimum of 12 months at each institution to complete their research.
Project information:Identification and characterization of microRNAs in the development of chemoresistant acute myeloid leukemia.
Drug resistance in patients with acute myeloid leukemia (AML) is a major hurdle for successful therapy. MicroRNA (miRNA) are small RNA with critical roles in most cellular processes that can promote diverse diseases when disrupted. Aberrant miRNA expression has been implicated in the development and maintenance of AML, however little is known about the specific role and clinical utility for miRNA in AML chemoresistance.
The Salmena (Toronto) and Kats (Melbourne) labs have developed advanced cellular and molecular tools, novel bioinformatic approaches and have access to mouse models of leukemia and human samples that will allow the identification and validation of miRNA that are critical for chemoresistance. This project represents fundamental work required to identify novel microRNA-associated therapeutic strategies to improve treatments for AML.
Click here for more information about the project. For information on how to apply, click here.
